Type: Contract
Job #38465

Our top pharmaceutical client is looking to add a Scientist II to their team!

Responsibilities:

You will join the protein expression and purification team in the department of Infectious Diseases and Vaccines (IDVax). This team generates critical protein reagents for internal IDVax programs in support of target discovery and validation in the early discovery space. The primary focus for this position will be large-scale (up to 10 L) expression of recombinant proteins and virus-like particles (VLPs) by transient transfection of suspension mammalian cells across multiple expression systems, including shake flask and WAVE bioreactor technology.

Preferred Skills:

• Experience with suspension mammalian cell cultures preferred.

• Experience with large-scale (up to 10L) cell culture and bioreactor technology, including WAVE bioreactor systems, preferred.

• Experience with cell culture analyzers, including the BioProfile FLEX analyzer.

• Experience developing optimized expression conditions for hard to express proteins, including multimeric proteins.

Minimum/Preferred Education Requirements:

• MS in biology, biochemistry or related scientific field with 6mos laboratory experience.

Or BS in biology, biochemistry or related scientific field with 2 or more years of relevant post-graduation work experience in a scientific setting, with preference given to industrial experience.

Qualifications:

• Solid foundation in sterile, aseptic technique and sterile cell culture.

• Experience working in a biosafety cabinet (BSC) for sterile cell culture.

• Experience with mammalian cell culture, including passaging cells, cell counting, determining cell density and dilutions.

• Experience with recombinant protein expression by transient transfection of mammalian cells.

• Proficiency in protein characterization techniques including SDS-PAGE, Western blot analysis, and UV-VIS spectroscopy.

• Detailed electronic notebook recordkeeping and meticulous maintenance of lab consumable and DNA inventories required.

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Equal Employment Opportunity (EEO) Information

While the position you're applying for may not be for a government role, Astrix is a governmental contractor and, as such, is required to collect certain information in its applicants. Astrix is an Equal Opportunity Employer and does not discriminate against any applicant for employment, or any employee because of age, color, sex, disability, national origin, race, religion, or veteran status. Completion of these fields will not affect your opportunity for employment or the terms or conditions of your employment.

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Scientist – II (Associate) – PA/NJ Only